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Fijs W B van Leeuwen Selected Research

cyanine dye 5

5/2021Translation of c-Met Targeted Image-Guided Surgery Solutions in Oral Cavity Cancer-Initial Proof of Concept Data.
1/2020Fluorescence background quenching as a means to increase Signal to Background ratio - a proof of concept during Nerve Imaging.
7/2019Click Chemistry in the Design and Production of Hybrid Tracers.
1/2018Tracers for Fluorescence-Guided Surgery: How Elongation of the Polymethine Chain in Cyanine Dyes Alters the Pharmacokinetics of a Dual-Modality c[RGDyK] Tracer.
1/2017Hybrid Imaging Labels: Providing the Link Between Mass Spectrometry-Based Molecular Pathology and Theranostics.
5/2015MMP-2/9-Specific Activatable Lifetime Imaging Agent.

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Fijs W B van Leeuwen Research Topics

Disease

35Neoplasms (Cancer)
09/2022 - 07/2007
22Prostatic Neoplasms (Prostate Cancer)
06/2022 - 11/2013
10Neoplasm Metastasis (Metastasis)
01/2022 - 10/2011
6Breast Neoplasms (Breast Cancer)
10/2019 - 07/2007
3Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/2022 - 12/2020
3Infections
01/2020 - 05/2015
3Carcinoma (Carcinomatosis)
06/2015 - 07/2012
2Cicatrix (Scar)
09/2022 - 06/2012
2Penile Neoplasms (Penile Cancer)
12/2020 - 03/2014
2Malaria
05/2019 - 01/2019
2Melanoma (Melanoma, Malignant)
05/2015 - 06/2012
2Multiple Myeloma
11/2007 - 09/2007
1Urinary Bladder Neoplasms (Bladder Cancer)
09/2022
1Musculoskeletal Diseases (Musculoskeletal Disease)
09/2021
1Vulvar Neoplasms (Vulvar Cancer)
12/2020
1Neurilemmoma (Schwannoma)
01/2020
1Schistosomiasis (Bilharziasis)
01/2020
1Schistosomiasis mansoni
01/2020
1Disease Progression
10/2019
1Tongue Neoplasms (Tongue Neoplasm)
01/2019
1Lymphatic Metastasis
01/2019
1Rupture
12/2018
1Acquired Immunodeficiency Syndrome (AIDS)
08/2017
1Ewing Sarcoma (Sarcoma, Ewing)
01/2017
1Polyps
08/2015
1Wounds and Injuries (Trauma)
05/2015
1Bacterial Infections (Bacterial Infection)
05/2015
1Adenocarcinoma
01/2011
1Prion Diseases (Transmissible Spongiform Encephalopathies)
04/2007

Drug/Important Bio-Agent (IBA)

11AntigensIBA
06/2022 - 01/2019
9Indocyanine Green (Cardio-Green)FDA LinkGeneric
09/2022 - 09/2010
8Coloring Agents (Dyes)IBA
12/2020 - 09/2010
7Peptides (Polypeptides)IBA
01/2017 - 10/2010
6cyanine dye 5IBA
05/2021 - 05/2015
5Biomarkers (Surrogate Marker)IBA
10/2021 - 01/2013
4Pentetic Acid (DTPA)FDA LinkGeneric
10/2019 - 05/2012
3Proteins (Proteins, Gene)FDA Link
01/2020 - 06/2012
3VaccinesIBA
01/2020 - 01/2019
3Chemokine ReceptorsIBA
01/2017 - 08/2011
3Fluorescent Dyes (Fluorescent Probes)IBA
08/2015 - 08/2011
2Biological ProductsIBA
03/2022 - 10/2021
2Radioisotopes (Radionuclides)IBA
09/2021 - 01/2019
2Blood Proteins (Serum Proteins)IBA
01/2020 - 07/2019
2LigandsIBA
01/2020 - 10/2019
2Antimicrobial PeptidesIBA
12/2019 - 05/2015
2IridiumIBA
02/2012 - 08/2011
2Docetaxel (Taxotere)FDA Link
04/2011 - 07/2007
2AlbuminsIBA
01/2011 - 09/2010
2Doxorubicin (Adriamycin)FDA LinkGeneric
03/2009 - 07/2007
2Proteasome InhibitorsIBA
11/2007 - 09/2007
1A-factor (Streptomyces)IBA
09/2022
1Radioactive TracersIBA
01/2022
1gallium 68 PSMA-11IBA
08/2020
1Pharmaceutical PreparationsIBA
01/2020
1Praziquantel (Biltricide)FDA Link
01/2020
1Lanthanoid Series Elements (Lanthanides)IBA
10/2019
1Prostate-Specific Antigen (Semenogelase)IBA
10/2019
1PSMA I&TIBA
01/2019
1MicellesIBA
12/2018
1RNA (Ribonucleic Acid)IBA
01/2017
1Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
01/2016
1Urokinase Plasminogen Activator ReceptorsIBA
06/2015
1Urokinase-Type Plasminogen Activator (Urokinase)FDA Link
06/2015
1Matrix Metalloproteinases (MMPs)IBA
05/2015
1ChloridesIBA
11/2013
1Radium-223IBA
11/2013
1SuspensionsIBA
01/2013
1Colloids (Colloid)IBA
06/2012
1Indicators and Reagents (Reagents)IBA
05/2012
1IntegrinsIBA
05/2012
1Fluorescein (Funduscein)FDA LinkGeneric
08/2011
1Fluorescein-5-isothiocyanate (FITC)IBA
08/2011
1isothiocyanic acidIBA
08/2011
1Annexin A5IBA
04/2011
1LuciferasesIBA
12/2010
1Member 1 Subfamily B ATP Binding Cassette TransporterIBA
03/2009
1tariquidar (XR9576)IBA
03/2009
1UbiquitinIBA
11/2007
1Proteasome Endopeptidase Complex (Proteasome)IBA
11/2007
1Bortezomib (Velcade)FDA Link
11/2007
1carfilzomibIBA
11/2007
1Cisplatin (Platino)FDA LinkGeneric
07/2007
1Prion ProteinsIBA
04/2007

Therapy/Procedure

10Prostatectomy (Retropubic Prostatectomy)
06/2022 - 10/2011
8Lymph Node Excision (Lymph Node Dissection)
06/2022 - 07/2016
6Therapeutics
01/2022 - 11/2007
5Computer-Assisted Surgery (Image Guided Surgery)
01/2022 - 05/2014
3Injections
09/2022 - 01/2011
3Intravenous Administration
01/2022 - 08/2015
2Intravenous Injections
01/2022 - 01/2019
2Gamma Cameras (Gamma Camera)
08/2017 - 03/2009
1Cystectomy
09/2022
1Robotic Surgical Procedures
01/2022
1Radiotherapy
01/2021
1Laser Therapy (Surgery, Laser)
10/2019
1Laparoscopes (Laparoscope)
01/2018
1Orthopedic Procedures
05/2015
1Aftercare (After-Treatment)
04/2011
1Transplantation
12/2010
1Drug Therapy (Chemotherapy)
07/2007